12/9/2023 0 Comments Saira naseem accident15 A recent study fromIndia demonstrated need of research with biomarkers and genetic studies to evaluate contributory environmental factors in ILD registries. 12- 14 House architecture with poor ventilation, home appliances like air-conditioners, carpets and kitchen’s smoke may also influence the status of this group of diseases. Residence near industrial area, food centers, animal farms, highways and farming sites may be greater risk environments in progression of the disease. The spectrum of ILDs may be dissimilar from other regions of the world attributable to standards of living, atmospheric conditions, occupational exposures, lifestyle, smoking habits, socio-cultural norms and cultivation practices in addition to the genetic profile. 8 The most common ILD, IPF, has a poor prognosis with median survival of 2-3 years from diagnosis 9 for other forms of ILDs, prognosis depends on the underlying and/or accompanying disease(s) but may be similarly poor. 4.75%, while 14.56% die due to pneumonia influenza. In Pakistan, ILDs are among the leading causes of mortality i.e. 5- 7 The majority of ILDs is idiopathic and includes the group of idiopathic interstitial pneumonias. 2- 4 Consequently, the accurate diagnosis of ILD requires a wide multidisciplinary approach based on assessment by a pulmonologist, a radiologist and sometimes a histopathologist with comprehensive expertise in handling the cases of ILD.įrom the studies, the most common ILDs are idiopathic pulmonary fibrosis (IPF), hypersensitivity pneumonitis (HP), sarcoidosis, ILD as a part of connective tissue disease (CTD), drug-induced ILD and pneumoconiosis. 1 Epidemiologic studies and archive reports on diagnoses of ILD have often been dependent on International Classification of Diseases (ICD) 9th edition codes, chronological databases, or diagnosis by a single physician that exhibited variable accuracy. There are more than 200 various manifestations of this condition based on clinical, radiological and histopathological findings. Interstitial lung disease (ILD) or diffuse parenchymal lung disease is characterized by inflammatory or fibrotic condition of the interstitium of lungs.
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